ADP inhibitors, also known as P2Y12 receptor inhibitors, are drugs that prevent ADP (adenosine diphosphate) from activating platelets, thus reducing platelet aggregation. This action helps to prevent blood clots. Examples of ADP inhibitors include:
- Clopidogrel
- Prasugrel
- Ticagrelor
- Ticlopidine
Mechanism of Action
ADP is a substance released from platelets that activates other platelets, leading to platelet aggregation. ADP inhibitors block the ADP receptor (P2Y12 receptor) on platelets, preventing this activation and reducing the formation of blood clots.
Table of ADP Inhibitors
| Drug | Mechanism |
|---|---|
| Clopidogrel | Blocks the P2Y12 receptor, preventing ADP-mediated platelet activation. |
| Prasugrel | Blocks the P2Y12 receptor, preventing ADP-mediated platelet activation. |
| Ticagrelor | Blocks the P2Y12 receptor, preventing ADP-mediated platelet activation. |
| Ticlopidine | Blocks the P2Y12 receptor, preventing ADP-mediated platelet activation. |
