Antifibrinolytic drugs are used to promote blood clotting.
These drugs work by preventing the breakdown of blood clots, thereby helping to control bleeding. They are often used in surgical settings to minimize blood loss and in other situations where excessive bleeding is a concern.
Examples of antifibrinolytic drugs include:
- Aprotinin: A serine protease inhibitor.
- Tranexamic acid (TXA): A synthetic lysine analog that prevents plasminogen from binding to fibrin.
- Epsilon-aminocaproic acid (EACA): Similar to TXA, it inhibits fibrinolysis.
- Aminomethylbenzoic acid: Another antifibrinolytic agent with a similar mechanism of action.
These drugs are typically administered intravenously or orally, depending on the specific medication and the clinical situation. Healthcare professionals determine the appropriate dosage and duration of treatment based on individual patient needs and the severity of bleeding.