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What Drugs Cause CRS?

Published in Pharmacology 1 min read

Several medications can induce Cytokine Release Syndrome (CRS), a systemic inflammatory response. Key examples include:

  • Rituximab: A CD20 antibody used to treat certain cancers and autoimmune diseases.
  • Tisagenlecleucel: A CD19 CAR T-cell therapy used to treat specific types of leukemia and lymphoma.
  • TGN1412 (Theralizumab): An experimental drug that caused severe CRS in a Phase I clinical trial.

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