Several medications can induce Cytokine Release Syndrome (CRS), a systemic inflammatory response. Key examples include:
- Rituximab: A CD20 antibody used to treat certain cancers and autoimmune diseases.
- Tisagenlecleucel: A CD19 CAR T-cell therapy used to treat specific types of leukemia and lymphoma.
- TGN1412 (Theralizumab): An experimental drug that caused severe CRS in a Phase I clinical trial.