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What are the Physiological Changes of Aging?

Published in Physiological Aging 3 mins read

Aging brings about a range of physiological changes in the body, affecting various systems and functions. These changes are primarily attributed to cellular and systemic alterations.

Key Physiological Changes

Here's a breakdown of some of the significant physiological changes that occur with aging, supported by the reference provided:

  • Loss of Cell Turnover: As we age, the rate at which our cells are replaced slows down. This can lead to decreased tissue repair and renewal.
    • For instance, skin becomes thinner and more prone to injury.
  • Decreased Function of Mucous Membranes: Mucous membranes, which protect various body openings, become less effective. This can result in dryness and increased susceptibility to infection.
    • Examples include dry eyes and a higher risk of respiratory infections.
  • Cachexia: This refers to a wasting syndrome characterized by weight loss, muscle atrophy, and fatigue. It is often seen in older adults and can significantly impact their quality of life.
  • Skeletal Muscle Mass Wasting: Known as sarcopenia, this is the age-related loss of muscle mass, strength, and function. This affects mobility, balance, and overall physical capability.
    • Practical Insight: Regular resistance exercises can help mitigate muscle loss.
  • Increased Atherosclerotic Decrease in Vascular Compliance: This refers to the stiffening of arteries due to plaque buildup, resulting in reduced elasticity and increased blood pressure. This elevates the risk of cardiovascular diseases.
    • Example: The arteries become less able to expand and contract with each heartbeat, leading to increased strain on the heart.
  • Cerebral Atrophy: This involves the shrinking of brain tissue, which can contribute to cognitive decline and changes in mental function.
    • Solutions: Keeping mentally active and maintaining a healthy lifestyle can help slow down cognitive decline.

Summary of Aging Physiological Changes

Change Impact
Loss of Cell Turnover Decreased tissue repair, thinner skin
Decreased Mucous Membrane Function Increased susceptibility to infections, dryness
Cachexia Wasting, muscle loss, fatigue
Skeletal Muscle Wasting Reduced strength, mobility, and balance
Decreased Vascular Compliance Increased blood pressure, cardiovascular risks
Cerebral Atrophy Cognitive decline, altered mental function

Overall Impact

These physiological changes, as highlighted in the reference, do not occur in isolation. They accumulate and contribute to the overall aging process. They also create a higher susceptibility to illness and a decreased functional capacity. Managing these changes requires a multi-faceted approach involving diet, exercise, and regular medical check-ups.

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