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How does lactic acid work?

Published in Physiology 3 mins read

Lactic acid, contrary to popular belief, isn't the villain behind muscle soreness. Instead, it plays a crucial role in cell respiration, glucose production, and molecular signaling. While its concentration increases in the blood during exercise, its function is more complex than just a waste product of intense activity.

Lactic Acid's Role in the Body

Lactic acid, or more accurately, lactate (as it exists in the body's pH), is a byproduct of anaerobic metabolism. This occurs when your body breaks down glucose for energy without sufficient oxygen. Let's break down its functions:

  • Energy Source: Lactate can be transported to the liver, where it's converted back into glucose through a process called the Cori cycle. This glucose can then be used for energy. Muscle cells can also directly use lactate as fuel.

  • Cell Respiration: Lactate is involved in cellular respiration, ensuring cells continue to have energy even when oxygen supply is limited.

  • Glucose Production: As mentioned above, the Cori cycle converts lactate back into glucose in the liver. This is crucial for maintaining blood sugar levels during intense activity.

  • Signaling Molecule: Lactate acts as a signaling molecule, influencing various physiological processes including:

    • Angiogenesis: The formation of new blood vessels.
    • Immune response: Modulating the activity of immune cells.
    • Muscle adaptation: Stimulating adaptations in muscle fibers to improve performance.

Lactate and Muscle Soreness

It's important to reiterate that lactate does not cause muscle soreness. Delayed onset muscle soreness (DOMS), which occurs 24-72 hours after intense exercise, is primarily caused by microscopic muscle damage and inflammation.

Lactic Acid Levels During Exercise

During intense exercise, the demand for energy exceeds the oxygen supply, leading to increased lactate production. This can result in:

  • Increased Blood Lactate Levels: Higher levels of lactate in the blood are normal during strenuous activity.
  • Hyperlactatemia: Abnormally elevated lactate levels in the blood.
  • Lactic Acidosis: A metabolic condition characterized by an excessive buildup of lactic acid in the body, leading to a decrease in blood pH. This is a serious condition often associated with underlying medical issues, not just exercise.

Summary

Lactic acid is not a waste product but an important molecule involved in energy production, glucose synthesis, and cell signaling. It does not cause muscle soreness. Elevated blood lactate levels are common during exercise, but extreme elevations leading to lactic acidosis are usually due to other underlying health conditions.

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