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Who produces albumin?

Published in Physiology 2 mins read

The liver is the organ that produces albumin.

Albumin is a protein made by the liver that circulates in the blood. It plays a crucial role in maintaining fluid balance within the bloodstream, transporting various substances like hormones, vitamins, and enzymes, and is also vital for tissue growth and repair. The liver synthesizes albumin at less than half its maximum capacity, indicating a reserve that can be utilized when needed.

Factors influencing albumin production include:

  • Protein and Amino Acid Nutrition: Adequate protein intake is essential for the liver to produce sufficient albumin. Amino acids are the building blocks of proteins, and their availability directly impacts albumin synthesis.
  • Colloidal Osmotic Pressure: Albumin contributes significantly to the colloidal osmotic pressure of the blood, which is the pressure that helps retain fluid within blood vessels.
  • Hormones: Certain hormones can influence albumin production.
  • Disease States: Liver diseases (such as cirrhosis and hepatitis) impair the liver's ability to synthesize albumin, leading to decreased levels in the blood. Kidney diseases can also lead to albumin loss.

Low albumin levels (hypoalbuminemia) can result in fluid accumulation in tissues (edema), impaired transport of essential substances, and compromised overall health.

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