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Do Platelets Contain Calcium?

Published in Platelet Composition 1 min read

Yes, platelets contain calcium.

Platelets, also known as thrombocytes, are small, anucleated cells in the blood that play a crucial role in hemostasis, the process of stopping bleeding. Calcium is essential for various platelet functions, including:

  • Platelet activation: Calcium ions are involved in the signaling pathways that trigger platelet activation in response to vascular injury.
  • Platelet adhesion: Calcium helps platelets adhere to the damaged blood vessel wall.
  • Platelet aggregation: Calcium is necessary for the aggregation of platelets, forming a platelet plug.
  • Clot stabilization: Calcium is a key component of the coagulation cascade, ultimately leading to the formation of a stable blood clot.

Published data confirms the presence of calcium in platelets, although precise figures can vary. According to Endres and Herget (reference 11), the calcium content of horse platelets was found to be 0.074 percent of dry weight. Furthermore, Haurowitz and Sladek (reference 12) reported finding 6.1 to 11.0 mg of calcium per 100 ml in platelets. These studies affirm that calcium is indeed a constituent of platelets, highlighting its importance for their normal functioning.

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