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What medication is used for needle stick injury?

Published in Post Exposure Prophylaxis 2 mins read

The medication used after a needle stick injury, if deemed necessary by a doctor, is Post-exposure prophylaxis (PEP), which involves antiretroviral drugs.

Understanding Post-Exposure Prophylaxis (PEP)

When a needle stick injury occurs, there's a risk of exposure to bloodborne pathogens like HIV. PEP is a preventive treatment that aims to reduce the risk of infection. It does not kill viruses but rather tries to prevent them from establishing themselves in the body.

How PEP Works

  • Antiretroviral Drugs: These medications are the primary component of PEP. They work by interfering with the virus's ability to replicate.
  • Time Sensitivity: PEP is most effective when started as soon as possible after the exposure incident, ideally within 72 hours.
  • Treatment Course: Typically, PEP involves a short course of these medications.

Key Considerations

Consideration Detail
Timing PEP should be started as soon as possible but no later than 72 hours after exposure for optimal effectiveness.
Effectiveness PEP reduces the risk of infection significantly, but it's not a 100% guarantee.
Type of Injury The decision to administer PEP is based on risk factors, such as the type of needle, the severity of the injury, and the source patient's status.
Side Effects Antiretroviral medications can have side effects, and it's important to discuss these with a healthcare professional.
Medical Evaluation A thorough medical evaluation is required to determine if PEP is necessary and appropriate. Blood tests might also be performed to assess the presence of infections.

Example Scenario

If a healthcare worker experiences a needle stick injury from a patient who is HIV-positive, PEP would be a necessary consideration and started within 72 hours.

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