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Which PPI is Best?

Published in PPI Effectiveness 1 min read

Based on the provided reference, pantoprazole and rabeprazole appear to be more effective than omeprazole and lansoprazole in decreasing heartburn.

PPI Effectiveness Comparison

The following table summarizes the findings from the referenced study regarding the effectiveness of different PPIs in reducing heartburn:

PPI Effectiveness in Decreasing Heartburn Comparison
Pantoprazole 100% More effective than omeprazole (86.9%, P < 0.05) and lansoprazole (82.4%, P = 0.0001).
Rabeprazole 100% More effective than omeprazole (86.9%, P < 0.05) and lansoprazole (82.4%, P = 0.005).
Omeprazole 86.9% Less effective than pantoprazole (100%, P < 0.05) and rabeprazole (100%, P < 0.05).
Lansoprazole 82.4% Less effective than pantoprazole (100%, P = 0.0001) and rabeprazole (100%, P = 0.005).

Considerations

While the reference indicates pantoprazole and rabeprazole were more effective in the study, it's important to remember:

  • This is based on a single study. More research may be available that presents different results.
  • Individual responses to medications can vary. What works best for one person may not be the best choice for another.
  • Consulting with a healthcare professional is always recommended to determine the most appropriate PPI for your specific needs and medical history.

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