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What is DIA in Pregnancy?

Published in Pregnancy Hormones 2 mins read

DIA, in the context of pregnancy, refers to dimeric inhibin A.

Understanding Dimeric Inhibin A (DIA)

Dimeric inhibin A, often shortened to DIA, is a hormone produced by the placenta during pregnancy. It’s a dimer, meaning it has two parts. Here’s what you should know about it:

Key Aspects of DIA

  • Production: The placenta is responsible for producing inhibin A.
  • Structure: It has two parts, which is why it is called "dimeric."
  • Hormone Type: It's classified as a hormone.

DIA Levels During Pregnancy

  • Changes Throughout Pregnancy:
    • DIA levels in maternal blood decrease slightly from 14 to 17 weeks of pregnancy.
    • After this period, DIA levels rise again.
  • Elevated Levels:
    • Higher than normal levels of DIA in the mother's blood are often seen in pregnancies where the fetus has Down syndrome.

Why is DIA Important?

DIA is a marker that can be used during prenatal screening. By monitoring DIA levels, doctors can gain insights into the health of the pregnancy. In particular, significant deviations from normal levels can prompt further diagnostic testing for conditions like Down syndrome.

Here's a summary table:

Aspect Description
Full Name Dimeric Inhibin A
Short Name DIA
Production Site Placenta
Structure Dimer (has two parts)
Level Fluctuations Decreases slightly (14-17 weeks), then increases
Significance May be elevated in pregnancies with Down syndrome fetus

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