The PAPP-A test is a prenatal blood test used to assess the health of the pregnancy.
Understanding the PAPP-A Test
The PAPP-A test, short for Pregnancy-associated Plasma Protein A, is a screening tool used during pregnancy, typically between 11 and 14 weeks. According to the provided reference, the test measures the levels of two hormones in the mother's blood:
- Pregnancy-associated Plasma Protein A (PAPP-A): A protein produced by the placenta.
- Human Chorionic Gonadotropin (hCG): A hormone also produced during pregnancy.
Why is the PAPP-A Test Important?
Monitoring PAPP-A levels helps assess the placental and fetal well-being. Abnormal levels can indicate a higher risk for certain chromosomal abnormalities in the baby, such as Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), or Patau syndrome (Trisomy 13). It's important to note that the PAPP-A test is a screening test, not a diagnostic test. Therefore, abnormal results warrant further investigation through diagnostic tests like chorionic villus sampling (CVS) or amniocentesis.
What Happens After the Test?
The results of the PAPP-A test, in conjunction with other factors like the nuchal translucency ultrasound, are used to calculate the risk of chromosomal abnormalities. If the risk is elevated, further testing and counseling are offered to the pregnant woman.
