The isoelectric point (pI) of human growth hormone (hGH) is approximately pH 5.
According to the provided reference, Human Growth Hormone (hGH) is a monomeric 22 kilo Dalton (kDa), 191 amino acid protein with an isoelectric point (pI) close to pH 5, produced in the anterior pituitary gland. This indicates that hGH is slightly acidic. The pI represents the pH at which the protein carries no net electrical charge.
