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What is the mechanism of digestion of proteins?

Published in Protein Digestion 2 mins read

Protein digestion is a multi-stage process that breaks down large protein molecules into smaller amino acid building blocks that the body can absorb. This process begins in the mouth and continues through the digestive tract, involving both mechanical and chemical breakdown.

Stages of Protein Digestion

1. Initial Mechanical Breakdown

  • Protein digestion begins with chewing in the mouth. Although saliva contains enzymes, they primarily focus on carbohydrates and fats rather than protein.
    • Amylase starts the digestion of carbohydrates.
    • Lipase starts the digestion of fats.

2. Protein Breakdown in the Stomach

  • Once food containing proteins reaches the stomach, the chemical digestion of proteins begins:

    • Hydrochloric Acid (HCl): The stomach releases hydrochloric acid, which unfolds or denatures the proteins. This makes them more accessible to the enzymes.
    • Proteases: These enzymes, such as pepsin, begin to break down proteins into smaller chains of amino acids called peptides.

Summary of the Process

Stage Location Actions
Chewing Mouth Mechanical breakdown; saliva starts carbohydrate & fat digestion, not protein.
Stomach Stomach Hydrochloric acid denatures proteins; proteases (e.g., pepsin) breaks proteins into peptides.

Example

Imagine eating a steak. Chewing starts the process, but the real protein breakdown starts in the stomach with hydrochloric acid and the enzyme pepsin, breaking the complex steak proteins into smaller peptide chains. These peptides will be further digested in the small intestine.

This process ensures that large proteins are broken down into their smaller, absorbable amino acid components.

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