Having large red blood cells, a condition called macrocytosis, isn't inherently a disease, but it can signal an underlying health issue that needs attention. According to information available as of September 16, 2024, macrocytosis is often linked to a deficiency of vitamin B12.
Understanding Macrocytosis
Macrocytosis indicates that your red blood cells are larger than normal. It's typically discovered during a routine blood test called a Complete Blood Count (CBC). The size of your red blood cells is measured by the Mean Corpuscular Volume (MCV).
| Measurement | Normal Range (approximate) |
|---|---|
| Mean Corpuscular Volume (MCV) | 80-100 femtoliters (fL) |
If your MCV is above the normal range, you may have macrocytosis.
Potential Underlying Causes
Since macrocytosis often signifies an underlying condition, it's crucial to investigate potential causes. A common cause is a deficiency in vitamin B12, which is essential for red blood cell production. Vitamin B12 is absorbed from the blood and stored in the liver. Other potential causes include:
- Folate deficiency: Similar to B12, folate is crucial for red blood cell formation.
- Liver disease: Liver problems can affect red blood cell size.
- Alcohol abuse: Excessive alcohol consumption can lead to macrocytosis.
- Hypothyroidism: An underactive thyroid can sometimes contribute to larger red blood cells.
- Certain medications: Some drugs can affect red blood cell size.
What to do if you have Macrocytosis
- Consult your doctor: It's crucial to discuss your blood test results with your doctor.
- Further testing: Your doctor may order additional tests to determine the underlying cause of the macrocytosis.
- Treatment: Treatment will depend on the underlying cause. For example, if you have a vitamin B12 deficiency, your doctor may recommend B12 supplements.
- Monitor: Regular blood tests may be needed to monitor your red blood cell size and the effectiveness of treatment.
