Yes, red blood cells produce lactate.
Lactate Production in Red Blood Cells
Lactate, also known as lactic acid, is created when pyruvate is metabolized without oxygen (anaerobically). According to research, red blood cells are among the tissues that produce the most lactate.
- Reference: Lactic acid, also called lactate, is a product of pyruvate metabolism under anaerobic conditions. The tissues that produce most lactic acid are the muscle cells and red blood cells.12-Oct-2022
Why Red Blood Cells Produce Lactate
Red blood cells (RBCs) lack mitochondria, which are necessary for aerobic respiration. Therefore, RBCs rely on anaerobic glycolysis for energy production. This process results in the production of lactate as a byproduct.
Lactate's Role and Fate
The lactate produced by red blood cells is not just waste. It can be:
- Transported to the liver for gluconeogenesis (the creation of glucose).
- Used as fuel by other tissues.
