According to Alma in the Book of Mormon, three of the most abominable sins in the sight of God are:
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Denying the Holy Ghost: This refers to rejecting the promptings and influence of the Holy Spirit, actively resisting its guidance, and hardening one's heart against divine communication. This is considered a grievous sin because it directly opposes the divine influence in one's life.
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Shedding innocent blood: This encompasses murder and the intentional taking of an innocent human life. The sanctity of human life is emphasized throughout many religious texts and traditions, making this a significant transgression.
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Committing sexual sin: This broadly encompasses sexual acts outside the bounds of God's divinely ordained plan, such as adultery, fornication, and other sexual immoralities. The violation of sacred covenants and the disregard for the purpose of sexual intimacy are considered profound sins. Adultery was specifically mentioned as one of these abominable sins.
It's important to note that the specific interpretation and application of these "unforgivable sins" can vary across different religious beliefs and perspectives. This answer focuses on the specific examples provided in the reference.