What are examples of renin inhibitors?
Examples of renin inhibitors include Aliskiren, Remikiren, Enalkiren, and VTP-27999, among others listed in drug databases.
Renin inhibitors are a class of medications designed to block the action of the enzyme renin, which plays a crucial role in the body's renin-angiotensin-aldosterone system (RAAS) and blood pressure regulation. By inhibiting renin, these drugs help lower blood pressure.
Based on the provided reference from DrugBank's Renin Inhibitors category, here are some specific examples:
| Drug Name | Description |
|---|---|
| Aliskiren | A direct renin inhibitor used to manage hypertension. |
| Remikiren | For the treatment of hypertension and heart failure |
| Enalkiren | Not Available (description) |
| VTP-27999 | VTP-27999 has been used in trials studying the basic science of Renal Function. |
These examples illustrate various stages of drug development and use, from a commercially available treatment like Aliskiren to compounds primarily studied in trials or with less information readily available.
