The cells that release renin are juxtaglomerular cells.
Renin Release: The Role of Juxtaglomerular Cells
Based on the provided information, the primary cells responsible for releasing the hormone-enzyme renin are the juxtaglomerular cells. These specialized cells play a crucial role in regulating blood pressure and fluid balance within the body.
How Juxtaglomerular Cells Work
Juxtaglomerular cells function as sensors within the kidney. According to the reference, they "manufacture and release the hormone-enzyme renin in response to minute changes in BP and the composition and volume of the extracellular fluid."
This means these cells are highly sensitive to conditions like:
- Changes in blood pressure (BP)
- Alterations in the composition of extracellular fluid
- Variations in the volume of extracellular fluid
When these conditions fall outside a specific range, the juxtaglomerular cells are stimulated to release renin.
Key Information Summary
Here's a quick overview of the key cell type involved:
| Cell Type | Function | Key Action |
|---|---|---|
| Juxtaglomerular cells | Act as sensors in the kidney | Manufacture and release renin |
The Importance of Renin Release
The release of renin is the first step in the Renin-Angiotensin-Aldosterone System (RAAS), a complex pathway that helps the body manage blood pressure, fluid volume, and electrolyte balance. By releasing renin in response to specific stimuli, juxtaglomerular cells initiate a cascade of events vital for maintaining homeostasis.
