Yes, an XXY female can get pregnant, although it is extremely rare.
While the typical chromosome configuration for females is XX, and males are XY, some individuals have variations. One such variation is XXY, often associated with Klinefelter syndrome in males. However, the provided reference highlights a highly unusual case:
- Extremely Rare Occurrence: Researchers identified a fertile female with a 47,XXY chromosome makeup who presented with a normal female phenotype and was pregnant. This finding is notable because it demonstrates that pregnancy is possible in XXY individuals assigned female at birth, albeit exceptionally rare.
This case is the first reported instance of a fertile XXY female with a normal appearance, showcasing that while rare, pregnancy can occur.
