The duration of chemotherapy for rhabdomyosarcoma (RMS) varies depending on the risk group and the specific treatment protocol. Generally, it involves a period of intensive chemotherapy followed by maintenance therapy.
Standard Chemotherapy Duration
For high-risk localized RMS, standard chemotherapy typically involves approximately 9 cycles of drugs like Ifosfamide, vincristine, actinomycin-D, with or without doxorubicin.
Maintenance Chemotherapy Duration
Following the initial chemotherapy, maintenance chemotherapy usually lasts for approximately 6 cycles. This often involves intravenous vinorelbine and daily oral cyclophosphamide.
| Chemotherapy Phase | Duration | Drugs Commonly Used |
|---|---|---|
| Standard Chemotherapy (Initial) | Approximately 9 cycles | Ifosfamide, vincristine, actinomycin-D +/− doxorubicin |
| Maintenance Chemotherapy | Approximately 6 cycles | Intravenous vinorelbine and daily oral cyclophosphamide |
It is crucial to consult with an oncologist for personalized treatment plans as chemotherapy duration and drug regimens can vary based on individual patient factors and specific clinical trial protocols.
