The four main types of rhabdomyosarcoma (RMS) are embryonal, alveolar, spindle cell/sclerosing, and pleomorphic.
Here's a breakdown of each type:
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Embryonal Rhabdomyosarcoma (ERMS): This is the most common type, primarily affecting children. It often occurs in the head and neck, genitourinary tract, or retroperitoneum. Embryonal RMS tends to have a better prognosis compared to other types.
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Alveolar Rhabdomyosarcoma (ARMS): This type is more frequently seen in older children and adolescents. It often occurs in the extremities, trunk, or perineum. Alveolar RMS can be more aggressive than embryonal RMS.
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Spindle Cell/Sclerosing Rhabdomyosarcoma: This is a less common variant. The spindle cell type typically occurs in paratesticular regions, while the sclerosing type appears in the extremities. Prognosis can vary depending on the specific features of the tumor.
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Pleomorphic Rhabdomyosarcoma: This type is predominantly found in adults and is relatively rare. It most commonly occurs in the extremities. Pleomorphic RMS is generally considered the most aggressive type of rhabdomyosarcoma.
