Restless legs syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder causing an overwhelming urge to move your legs, often accompanied by uncomfortable sensations. While the exact cause remains unknown in most cases, several factors are implicated.
Potential Causes of Restless Legs Syndrome
- Genetics: RLS often runs in families, suggesting a genetic component. Specific gene variants have been linked to the condition. [Source: NIH, Mayo Clinic]
- Brain Iron Deficiency: Low levels of iron in the brain may play a role in developing RLS. [Source: NIH]
- Dopamine Dysfunction: RLS may be related to a dysfunction in the brain's dopamine system, which controls movement. [Source: NHS]
- Other Underlying Health Conditions: Certain medical conditions, like iron deficiency anemia, kidney failure, and diabetes, can increase the risk of RLS. [Source: NHS, WebMD]
Symptoms and Impact
The primary symptom is an irresistible urge to move the legs, typically accompanied by uncomfortable sensations described as creeping, crawling, itching, or pulling. These sensations worsen during rest and improve with movement. RLS significantly impacts sleep quality and overall well-being, reducing quality of life for affected individuals. [Source: Mayo Clinic, NIH]
Note: The information above summarizes findings from multiple reliable sources. Specific causes and contributing factors can vary among individuals. For a proper diagnosis and treatment plan, consultation with a healthcare professional is essential.
