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What Causes RMS Disease?

Published in RMS Causes 2 mins read

The term "RMS disease" is ambiguous and refers to two distinct conditions: Rhabdomyosarcoma (RMS), a type of cancer, and Relapsing-Remitting Multiple Sclerosis (RRMS), a neurological disorder. Therefore, the cause of "RMS disease" depends on which condition is intended.

Rhabdomyosarcoma (RMS)

The exact cause of rhabdomyosarcoma (RMS) is currently unknown. While there are no widely understood causes for most cases, researchers are actively studying how genetic changes in DNA contribute to the development of this cancer. Certain genetic syndromes, such as Li-Fraumeni syndrome, Beckwith-Wiedemann syndrome, neurofibromatosis, Costello syndrome, and cardiofaciocutaneous syndrome, are associated with an increased risk of developing RMS. These syndromes often involve inherited genetic changes.

  • Key Point: The development of RMS is not fully understood, but genetic factors play a significant role.

Relapsing-Remitting Multiple Sclerosis (RRMS)

Relapsing-Remitting Multiple Sclerosis (RRMS) is a progressive disease that damages the central nervous system (CNS). The precise cause of RRMS is not definitively known, but scientists believe that a combination of genetic predisposition and environmental factors likely plays a crucial role. Genetic susceptibility increases the risk, and some researchers suspect that infections may be a contributing factor.

  • Key Point: RRMS is thought to result from a combination of genetic susceptibility and environmental triggers, potentially including infections.

Therefore, it's crucial to clarify which "RMS" is being referred to when discussing its cause. The causes are currently different and remain an area of ongoing research for both diseases.

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