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Which Gland Produces the Most Saliva?

Published in Salivary Gland Function 1 min read

The answer depends on whether the salivary glands are stimulated or not.

Unstimulated Saliva Production

In the resting state (unstimulated), the submandibular glands produce the most saliva, contributing approximately 70% of the total unstimulated salivary output. This is supported by multiple sources [3, 7].

Stimulated Saliva Production

However, when stimulated, such as during eating, the parotid glands become the major saliva producers, contributing more than 50% of the total saliva. This is confirmed by several studies [3]. While the parotid glands are the largest salivary glands [2], their contribution to overall saliva production changes significantly with stimulation. In the resting state, they contribute a smaller percentage (around 10%) [4], but this increases dramatically during eating.

Summary of Salivary Gland Contributions

Here's a summary table to illustrate the differences:

Gland Unstimulated Saliva Production (%) Stimulated Saliva Production (%)
Submandibular ~70% <50%
Parotid ~10% >50%
Sublingual The remaining percentage The remaining percentage

Therefore, there isn't a single definitive answer to the question. The gland producing the most saliva depends on whether the glands are stimulated or at rest.

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