The stratum spinosum, also known as the spinous layer or prickle cell layer, is a layer of the epidermis located between the stratum granulosum and stratum basale. This layer is composed of polyhedral keratinocytes, which are connected by desmosomes. The stratum spinosum is responsible for cell division and the production of keratin, a protein that gives skin its strength and elasticity.
- Keratinocytes: The main cell type in the stratum spinosum, these cells are responsible for producing keratin, which is a protein that strengthens and protects the skin.
- Desmosomes: These are specialized cell junctions that hold keratinocytes together, giving the skin its structural integrity.
- Cell Division: The stratum spinosum contains cells that divide and produce new keratinocytes, constantly replacing the older cells that are shed from the surface of the skin.
Key Features of the Stratum Spinosum:
- Location: Between the stratum granulosum and stratum basale.
- Cell Type: Composed primarily of keratinocytes.
- Functions: Involved in cell division, keratin production, and structural integrity of the skin.
