The two most basic barrier functions of skin are:
- Maintaining an "inside-outside" barrier regulating water loss: This means the skin helps to prevent the body from losing too much moisture and drying out. This is essential for maintaining hydration and preventing skin damage.
- Maintaining an "outside-inside" barrier protecting the organism from external harm: This means the skin acts as a shield against the environment, protecting the body from things like bacteria, viruses, chemicals, and physical injury.