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What are corneocyte cells?

Published in Skin Biology 1 min read

Corneocyte cells are the flattened, dead cells that make up the outermost layer of your skin, called the stratum corneum. They are essentially protein bricks with a tough, protective envelope that helps keep your skin hydrated and prevents harmful substances from entering your body.

Here's a breakdown of their key features:

  • Terminal Differentiation: They are the final stage of keratinocytes, the main cells that make up your skin.
  • Keratin-filled: They are packed with keratin, a tough protein that gives your skin its strength and flexibility.
  • No Organelles: They lack any living components like a nucleus or mitochondria.
  • Protective Barrier: Their tough structure forms a barrier that prevents water loss and keeps out harmful substances.
  • Desquamation: They are constantly shed and replaced by new cells from below, maintaining the skin's integrity.

Corneocytes are essential for maintaining the skin's barrier function and protecting it from damage. They play a vital role in keeping your skin healthy and resilient.

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