Taking a skin cell sample is a common procedure known as a skin biopsy. This involves removing a small piece of skin for examination under a microscope. The method used to collect the sample depends on the location and type of skin condition being investigated.
Here are some common techniques used to collect skin cell samples:
- Punch Biopsy: This method involves using a small, circular tool called a punch to remove a core of skin. This technique is commonly used for diagnosing skin cancers.
- Shave Biopsy: A razor is used to scrape off a thin layer of skin for examination. This method is often used for diagnosing conditions affecting the outer layer of skin, like psoriasis.
- Excisional Biopsy: A larger piece of skin is surgically removed, often including the entire lesion. This method is used for diagnosing more complex skin conditions and for obtaining tissue for further testing.
- Fine-Needle Aspiration (FNA): A thin needle is inserted into the skin lesion to collect a small sample of cells. This method is often used to diagnose lumps beneath the skin's surface.
The collected sample is then sent to a laboratory for analysis. A pathologist will examine the sample under a microscope to identify any abnormalities and determine the cause of the skin condition.
Reference:
The reference provides detailed instructions for collecting skin samples for research purposes, particularly for preserving the sample for further processing. It includes steps like cutting the skin into 2mm × 2mm squares, placing it dermis-side down in a cryomold, and adding OCT compound to cover the sample. While this reference is specific to research, it provides insight into the general process of collecting skin samples.
