Keratinocytes are also known as squamous cells.
Understanding Keratinocytes and Their Other Name
Keratinocytes are the predominant cell type in the epidermis, the outermost layer of skin. They are responsible for producing keratin, a tough protein that protects the skin, hair, and nails. As keratinocytes mature and move upwards through the epidermal layers, they change in shape and function. In the upper layers of the epidermis, these mature keratinocytes are referred to as squamous cells, reflecting their flattened, scale-like appearance. Therefore, while "keratinocyte" is the primary and more precise term describing these cells and their function, "squamous cell" is another accurate name for these cells in their mature state within the epidermis.
Several sources confirm this alternate terminology:
- Reference 1: "...these maturing cells are now called squamous cells, or keratinocytes." This directly states the interchangeability of the terms in the context of mature epidermal cells.
- Reference 3: "The keratinocytes from the squamous layer are then pushed up..." This implies the layers containing squamous cells are comprised of keratinocytes.
- Reference 4: "...dead keratinocytes (anucleate squamous cells)..." This indicates mature keratinocytes are described as squamous cells.
While "keratinocyte" emphasizes the cell's function (keratin production), "squamous cell" highlights its morphology (flattened shape). Both names accurately refer to the same cell type at different stages of maturation.
