Skin BP can refer to several things, depending on the context. Let's explore the possibilities:
1. Bullous Pemphigoid (BP)
- Definition: Bullous pemphigoid (BP) is a chronic autoimmune skin disease. It causes large, fluid-filled blisters to develop on the skin. The condition mainly affects older people and is characterized by an itchy, raised rash that progresses to blistering. [Source: https://www.nhs.uk/conditions/bullous-pemphigoid/ and https://www.aocd.org/page/BullousPemphigoid]
- Symptoms: Itchy, raised rash, progressing to large blisters.
- Treatment: Treatment can help manage the condition, but it can last for several years and sometimes cause serious complications, such as skin infections leading to sepsis, or side effects from steroid treatment, including high blood pressure. [Source: https://www.nhs.uk/conditions/bullous-pemphigoid/]
2. Blood Pressure (BP) and Skin Sodium Content
- Definition: There's a correlation between skin sodium content and blood pressure. Studies suggest that skin acts as a reservoir for sodium, potentially influencing blood pressure regulation. Elevated skin sodium has been observed in patients with treatment-resistant hypertension. [Source: https://www.nature.com/articles/s41440-023-01450-4, https://pmc.ncbi.nlm.nih.gov/articles/PMC9685327/, and https://www.jci.org/articles/view/60113]
- Mechanism: The mononuclear phagocyte system (MPS) cells in the skin seem to play a role in regulating electrolyte balance, influencing overall blood pressure. [Source: https://www.jci.org/articles/view/60113]
- Significance: Skin sodium content might serve as a predictor of blood pressure response to treatment, and could indicate an additional buffering system in response to salt changes. [Source: https://www.nature.com/articles/s41440-023-01450-4 and https://pmc.ncbi.nlm.nih.gov/articles/PMC9685327/]
3. Aqueous Cream BP (British Pharmacopoeia)
- Definition: Aqueous Cream BP is a type of emollient cream formulated according to British Pharmacopoeia standards. It is used to moisturize and soothe dry skin. However, there are reports that in individuals with a history of atopic dermatitis (AD), its application can damage the skin barrier. [Source: https://pubmed.ncbi.nlm.nih.gov/21564067/]
- Caution: Not suitable for everyone, particularly those with a history of atopic dermatitis (AD).
