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What Substances Are Excreted Through the Skin?

Published in Skin Excretion 2 mins read

The skin excretes a variety of substances, far beyond just water and salts.

Excretory Function of the Skin

The skin, our largest organ, plays a crucial role in excretion. While commonly known for perspiration (sweating), its excretory capabilities extend to a surprisingly wide range of substances. According to research, skin excretion is not limited to just water, potassium, sodium, and urea.

Substances Excreted by the Skin

The following table lists a variety of substances that are excreted through the skin:

Substance Category Examples
Electrolytes Potassium, Sodium
Nitrogenous Wastes Urea, Creatinine, Amino Acids
Minerals Calcium, Phosphorus
Organic Acids Lactic Acid, Pyruvic Acid
Hormones & Mediators Histamine, Prostaglandins
Energy Substrates Glucose
Foreign Substances Drug substances, Heavy metals

Examples and Practical Insights:

  • Sweat Composition: The composition of sweat isn't solely water. It reflects the body’s internal environment, including waste products and electrolytes.
  • Detoxification: The skin aids in the removal of certain heavy metals and drug metabolites, though this is not its primary detox function, which is primarily performed by the liver and kidneys.
  • Individual Variations: The specific substances and their amounts excreted can vary among individuals, influenced by factors like diet, hydration, physical activity, and health conditions.

In addition to these substances, the skin also plays a role in the secretion of sebum, an oily substance that helps to keep the skin lubricated and protected.

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