Fibrosis in the skin is characterized by an abnormal increase of fibrous connective tissue in the dermis or subcutis, often as a result of injury and chronic inflammation.
Understanding Skin Fibrosis
Skin fibrosis, also known as dermal fibrosis, refers to the excessive accumulation of connective tissue in the skin. This process can alter the skin's structure and function, often leading to thickening, hardening, and scarring.
Causes of Skin Fibrosis
According to the provided reference, fibrosis is often a consequence of:
- Epidermal or dermal injury: Trauma to the skin can trigger the fibrotic process.
- Chronic chemical exposure: Prolonged contact with certain chemicals can induce fibrosis.
- Chronic inflammation: Persistent inflammation in the skin can lead to increased connective tissue deposition.
These factors can lead to an increase of fibrous connective tissues in the dermis or subcutis.
Characteristics of Skin Fibrosis
Fibrosis in the skin typically accompanies chronic inflammation and is characterized by:
- Increased fibrous connective tissue: This is the hallmark of fibrosis.
- Location: Primarily occurs in the dermis or subcutis.