Yes, antibodies are found in the skin. IgA, IgM, and IgG are present in the stratum corneum, the outermost layer of the skin. These antibodies play a crucial role in defending the skin against pathogens and maintaining its health.
They are produced by antibody-secreting cells (ASCs) located near eccrine glands. These antibodies are then transported across the eccrine gland lumen into sweat and sebum, eventually being secreted onto the skin's surface.