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What causes deficiency of melanin?

Published in Skin Pigmentation Disorders 2 mins read

A deficiency in melanin can lead to several disorders and diseases. For instance, a complete absence of melanin causes a condition called albinism. Vitiligo is another condition caused by a deficiency of melanin, where the cells that produce melanin die or stop functioning, resulting in patches of light skin.

While the exact cause of vitiligo is unknown, research suggests it could be an autoimmune condition where the immune system mistakenly attacks melanocytes, the cells responsible for producing melanin.

Other potential causes of melanin deficiency include:

  • Vitamin B12 deficiency: This can disrupt the balance of melanocytes and lead to a decrease in melanin production.
  • Genetic mutations: Albinism, for example, is caused by genetic mutations that affect the production of melanin.

The lack of melanin can have several consequences, including:

  • Increased sensitivity to sunlight: Melanin protects the skin from harmful UV radiation. Without it, the skin is more susceptible to sunburn and other skin damage.
  • Psychological effects: People with vitiligo may experience low self-esteem due to changes in their appearance.

It is important to consult a doctor if you suspect you have a melanin deficiency. Treatment options may include:

  • Topical medications: These can help to stimulate melanin production.
  • Light therapy: This involves exposing the skin to ultraviolet light to stimulate melanin production.
  • Surgery: In some cases, surgery may be used to transplant melanocytes to areas of skin that have lost pigment.

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