Yes, BRUH is considered unisex.
While originally rooted in Black English and often used as a term of address between men, particularly Black men, the term "bruh" has expanded in usage. It is now commonly used by both young men and young women, especially among younger generations.
This wider adoption means its use isn't strictly limited by gender. Therefore, "bruh" can be considered a unisex term, particularly in informal settings and among specific demographic groups.