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How can smoking damage ciliated cells?

Published in Smoking and Cilia 2 mins read

Smoking damages ciliated cells primarily through harmful chemicals that cause paralysis.

The Impact of Smoking on Ciliated Cells

Ciliated cells, which line the airways, play a vital role in clearing mucus and debris from the lungs. Smoking severely compromises this function.

Here’s a breakdown:

  • Paralysis of Cilia: Cigarette smoke contains harmful chemicals that paralyse these cilia, leading to a build-up of mucus. This paralysis prevents the cilia from effectively sweeping away irritants and pathogens.
  • Irritation and Inflammation: Smoke irritates the bronchi, causing bronchitis and inflammation. This inflammation further impairs ciliary function.

Consequences of Ciliary Damage

When cilia are damaged, several health problems can arise:

  • Smoker's Cough: The build-up of mucus due to paralyzed cilia results in a persistent cough, commonly known as a smoker's cough.
  • Increased Risk of Infection: With impaired mucus clearance, the lungs become more susceptible to infections, such as pneumonia and bronchitis.
  • Chronic Bronchitis: Long-term irritation and inflammation of the bronchi lead to chronic bronchitis.
  • Increased Cancer Risk: The accumulation of carcinogens in the lungs, due to the failure of ciliary clearance, increases the risk of lung cancer.

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