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What is the difference between splenomegaly and massive splenomegaly?

Published in Splenomegaly Differences 1 min read

The primary difference between splenomegaly and massive splenomegaly lies in the degree of spleen enlargement.

Feature Splenomegaly Massive Splenomegaly
Spleen Weight 400-500 g More than 1000 g
Largest Dimension (Poulin et al.) 11-20 cm (moderate) Greater than 20 cm (severe)
Definition Enlargement of the spleen Significant/Severe enlargement of the spleen

As illustrated in the table, splenomegaly indicates a general enlargement of the spleen, where the spleen weight ranges from 400-500g, or the largest dimension is 11-20cm according to Poulin et al. In contrast, massive splenomegaly signifies a much more pronounced enlargement, with the spleen weighing over 1000g or having a largest dimension greater than 20cm as defined by Poulin et al.

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