Yes, Stiff Person Syndrome (SPS) does affect the brain, as it primarily impacts the central nervous system.
SPS is a progressive autoimmune disorder. According to information from October 13, 2022, it affects the central nervous system, mostly the brain and spinal cord. The disease initially manifests as rigidity in the muscles of the trunk, which can then spread throughout the body.
Here's a breakdown:
- Central Nervous System Impact: SPS directly targets the CNS, which includes both the brain and spinal cord.
- Autoimmune Nature: As an autoimmune disorder, SPS involves the immune system mistakenly attacking healthy nerve cells.
- Progressive Condition: SPS symptoms tend to worsen over time, reflecting the ongoing damage to the nervous system.
- Initial Symptoms: Muscle rigidity, especially in the trunk, is a common early indicator.
- Widespread Effects: Over time, rigidity and other symptoms can spread to other parts of the body, further demonstrating the systemic impact on the nervous system controlled by the brain and spinal cord.