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Are Cheek Cells Stem Cells?

Published in Stem Cell Research 2 mins read

Cheek cells themselves are not stem cells; however, facial skin, including areas near the cheek, contains cells with stem cell-like properties.

Facial Skin and Stem Cell-Like Cells

While differentiated cheek cells scraped during a buccal swab are not stem cells, human adult facial skin contains skin-derived precursor (SKP) cells, and these SKP cells exhibit characteristics of stem cells. This suggests that facial skin is a source of cells with stem cell-like properties, but specifically mature cheek cells are not themselves stem cells.

Characteristics of Facial SKP Cells

Facial SKP cells show several key features associated with stem cells:

  • Differentiation Potential: Facial SKP cells can differentiate into neural and mesodermal cells.
  • Stem Cell Marker Expression: Facial SKP cells express undifferentiated stem cell markers, including Sox9, indicating their stem cell-like nature.
  • Source for Tissue Engineering: Because of these properties, facial skin is considered a useful source of stem cells for tissue engineering applications.

Table Summarizing Facial SKP Cells

Feature Description
Cell Type Skin-derived precursor (SKP) cells
Location Human adult facial skin
Differentiation Potential Can differentiate into neural and mesodermal cells
Markers Express undifferentiated stem cell markers (e.g., Sox9)
Potential Applications Useful source of stem cells for tissue engineering applications

In conclusion, while cheek cells scraped from inside your mouth aren't stem cells, facial skin contains SKP cells with stem cell-like characteristics and the potential to differentiate into various cell types. Therefore, facial skin can be considered a source of cells with stem cell-like properties.

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