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What Procedure is PPD?

Published in Tuberculosis Screening Procedure 3 mins read

PPD refers to the Purified Protein Derivative, which is the solution utilized in a diagnostic procedure commonly known as the tuberculin skin test.

This procedure is a standard method used to screen for latent tuberculosis infection. It involves a specific technique for administering the solution and observing the body's reaction.

Understanding PPD and the Associated Procedure

The term "PPD" itself is not the procedure, but rather the solution used within the procedure. The procedure is the tuberculin skin test.

What is PPD?

PPD, or **Purified Protein Derivative**, is a sterile solution derived from cultures of *Mycobacterium tuberculosis*. It does not contain live bacteria, meaning it cannot cause tuberculosis infection. Instead, it contains proteins from the bacteria that can elicit an immune response in individuals who have been exposed to TB.

Alternative Names for the Test

You may hear the PPD test referred to by several other names, all describing the same diagnostic procedure:
  • Tuberculin Skin Test
  • TB Test
  • Mantoux Test

The PPD Procedure Explained

The procedure for administering the PPD test is precise and involves the following steps:
  • Injection Site: A small amount of the PPD solution is injected into a specific location on the body.
  • Method: The injection is administered with a needle, right under the skin of the inner forearm. This is an intradermal injection, creating a small, raised wheal (or blister-like bump) on the skin's surface.
  • Solution Amount: Only a small, standardized amount of the solution is used.
  • Reading the Results: After 48 to 72 hours, a healthcare professional examines the injection site for a reaction, specifically the size of any induration (a hard, raised area), to determine if the test result is positive or negative.

Key Aspects of the PPD Procedure

To further clarify, here's a quick overview of the essential components related to PPD:

Aspect Description
PPD (Solution) Purified Protein Derivative, the liquid used for the test.
Procedure Names Tuberculin Skin Test, TB Test, Mantoux Test.
Injection Method Intradermal (right under the skin).
Injection Location Inner forearm.
Purpose To screen for latent tuberculosis infection.

This procedure is a crucial tool in public health for identifying individuals who may have been exposed to tuberculosis and require further evaluation or treatment.

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