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Are Tumors Dead Cells?

Published in Tumor Biology 1 min read

No, tumors are not entirely composed of dead cells; they are complex masses containing both living and dead cells.

While some parts of a tumor, particularly the necrotic core, may contain dead or dying cells, the entire tumor is not a collection of dead cells. A necrotic core, while predominantly dead, might still contain some living cells. According to research, even in a necrotic region, "not all the cells are dead."

Here's a breakdown:

  • Tumor Composition: Tumors are composed of a mixture of cells, including:
    • Living, actively dividing cancer cells.
    • Supportive cells (e.g., blood vessel cells, immune cells).
    • Dead or dying cells (especially in the center of larger tumors).
  • Necrotic Core: The center of a rapidly growing tumor may outstrip its blood supply, leading to cell death (necrosis). However, this necrotic core is not uniformly dead.
  • Importance of Living Cells: The living cancer cells are responsible for tumor growth, spread (metastasis), and resistance to treatment.

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