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What is the first drug for ulcerative colitis?

Published in Ulcerative Colitis Treatment 1 min read

The first drug typically offered for mild-to-moderate ulcerative colitis is a 5-ASA (5-aminosalicylic acid).

5-ASA for Ulcerative Colitis: A Detailed Look

5-ASA medications are a class of drugs commonly used to treat ulcerative colitis. They work by reducing inflammation in the lining of the colon.

Forms of 5-ASA

According to the provided reference, 5-ASA is initially given in:

  • Suppository form
  • Enema form

These forms are often the first line of treatment for mild-to-moderate ulcerative colitis, targeting the inflammation directly in the rectum and lower colon.

What Happens If Symptoms Don't Improve?

If symptoms do not improve after approximately 4 weeks using suppositories or enemas, doctors may prescribe 5-ASA in other forms. The reference mentions:

  • Tablets
  • Capsules

These oral forms of 5-ASA allow the medication to reach different parts of the colon, providing a broader anti-inflammatory effect.

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