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How effective are vaccines?

Published in Vaccine Effectiveness 2 mins read

Vaccines are generally very effective at preventing disease. The exact effectiveness can vary depending on the specific vaccine and the disease it protects against.

COVID-19 Vaccine Efficacy Example

Here's an example based on the provided reference regarding COVID-19 vaccines:

Vaccine Efficacy Rate
Moderna ~95%
Pfizer-BioNTech ~95%

According to initial Phase 3 clinical data from December 2020, both Moderna and Pfizer-BioNTech vaccines demonstrated about 95% efficacy in preventing COVID-19. This means individuals who received these vaccines were significantly less likely to contract the disease compared to those who did not.

General Vaccine Effectiveness Considerations

While the COVID-19 vaccine example provides a specific instance, it's important to remember:

  • Different vaccines, different efficacy: Efficacy rates vary from vaccine to vaccine. Some vaccines may be closer to 100% effective, while others may be lower.
  • Waning immunity: Over time, the protection offered by some vaccines can decrease. Booster shots can help restore immunity.
  • Real-world effectiveness vs. clinical trials: Clinical trial efficacy rates may not always perfectly reflect real-world effectiveness. Factors like the spread of new variants, individual health, and adherence to public health measures can all influence how well a vaccine works in practice.
  • Severity of disease: Even if a vaccine doesn't completely prevent infection, it can often significantly reduce the severity of the illness.

In summary, vaccines are a highly effective tool for preventing infectious diseases, although their effectiveness can vary based on several factors.

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