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What is a Painful Vaccine?

Published in Vaccine Side Effects 2 mins read

A painful vaccine, based on the provided information, is primarily associated with the pertussis vaccine, specifically when it's part of the DTwP combination.

Understanding Vaccine Pain

While all vaccines can cause some mild discomfort, certain vaccines are known to produce more noticeable and intense side effects. The DTwP vaccine is highlighted as the most likely to cause significant discomfort among the recommended vaccines.

DTwP Vaccine

The DTwP vaccine is a combination vaccine that protects against:

  • Diphtheria
  • Tetanus
  • Pertussis (whooping cough)

According to the reference, it is the pertussis component within DTwP that is most likely to cause pain and other reactions.

Side Effects of Painful Vaccines

Reactions to the pertussis vaccine within DTwP can include:

  • Severe Pain: Significant discomfort at the injection site.
  • Fever: An elevated body temperature.
  • Vomiting: Feeling sick and throwing up.
  • Swelling: Visible swelling around the area where the vaccine was given.
  • Redness/Inflammation: Redness and inflammation at the injection site.


Vaccine Pain Level Potential Side Effects
DTwP High Pain, fever, vomiting, swelling, redness
Others Low Mild pain, slight redness


Important Note: These reactions are generally temporary and do not indicate a serious problem. However, if the reaction is severe or persistent, it is important to seek medical advice.


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