The most painful vaccine is subjective and can vary based on individual sensitivity and the type of vaccine. However, some vaccines are known to cause more injection site pain than others.
Several studies and sources suggest that the pneumococcal vaccine (PCV) is one of the most painful vaccines.
- One study found that the PCV vaccine caused more pain than the combined Diphtheria, Tetanus, Pertussis, Haemophilia Influenza B (DPTaP-Hib) vaccine.
- Other sources also list the PCV vaccine, along with MMR and HPV vaccines, as being among the most painful.
It's important to note that the pain experienced from vaccines can also depend on factors like:
- Injection method: Deeper injections into muscle tissue tend to be more painful.
- Vaccine ingredients: Some vaccine ingredients can cause more irritation or inflammation.
- Individual sensitivity: Some people may experience more pain than others due to genetics or age.
To minimize discomfort, it's generally recommended to administer the most painful vaccine last when multiple injections are needed.
