Yes, the game Hades features LGBT characters and themes.
The protagonist, Zagreus, is pansexual, demonstrated by his ability to pursue romantic relationships with both Megara and Thanatos simultaneously. The game acknowledges and explores the concept of polyamory through character interactions and dialogue. This makes Hades a game that explicitly includes LGBT representation, and specifically, bisexual/pansexual representation. While Hades himself is not a romance option, the world he inhabits and the characters within it are decidedly LGBT-inclusive.
