JC in medical terms refers to the John Cunningham virus (JCV), also known as human polyomavirus 2. This common virus infects most people by the age of 10, usually without causing any noticeable symptoms. While JCV typically remains inactive in the body, it's important to note that it can cause a serious condition called progressive multifocal leukoencephalopathy (PML) in individuals with weakened immune systems.
Understanding JCV
- Prevalence: The majority of people are infected with JCV by age 10.
- Typical Symptoms: Most infections are asymptomatic (show no symptoms).
- Reactivation Risk: JCV reactivation and subsequent disease (like PML) is primarily a concern for individuals with compromised immune systems, such as those with HIV/AIDS or undergoing certain immunosuppressive treatments.
The provided reference states: "The John Cunningham virus, or JC virus (JCV), causes PML. JCV is also known as human polyomavirus 2. By age 10, most people have been infected with JCV, but it rarely causes symptoms. The virus remains in the body, but normally is inactive and causes no problems."
