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Do viruses have a capsule?

Published in Viral Structures 2 mins read

Viruses do not have a capsule; they have a capsid.

While the terms may sound similar, capsules and capsids are different structures with different functions. Viruses possess a protein capsid to protect their nucleic acid genome. Here's a breakdown:

Virus Structure: Capsid vs. Capsule

Feature Capsid Capsule
Definition A protein shell surrounding the viral genome. A gelatinous outer layer found in some bacteria and fungi.
Composition Protein subunits (capsomeres). Polysaccharides or polypeptides.
Function Protects the viral genetic material. Protection, adherence, and avoidance of immune response.
Location Directly surrounds the nucleic acid. Outermost layer beyond the cell wall (in bacteria).
Presence Present in all viruses. Not present in viruses, mainly in bacteria and fungi.

Understanding the Viral Capsid

The viral capsid is essential for the survival and infectivity of a virus. According to the reference provided, capsids come predominantly in two shapes:

  • Helical: A spiral shape that curves cylindrically around an axis.
  • Icosahedral: A polyhedral shape with 20 faces.

Key Functions of the Capsid:

  • Protection: Shields the viral genetic material (DNA or RNA) from degradation by enzymes or physical damage in the external environment.
  • Delivery: Facilitates the binding and entry of the virus into the host cell.
  • Specificity: Helps in determining which host cells the virus can infect.

Example of a Capsid

  • The Tobacco mosaic virus uses a helical capsid, forming a rod-like structure.

Capsule vs. Capsid: Key Differences

It is crucial to understand the difference between these terms:

  • Capsules are found primarily in bacteria and fungi. They are typically composed of polysaccharides and help in protection, adhesion, and immune evasion.
  • Capsids, as detailed in the reference, are unique to viruses and are protein structures that surround their genetic material.

In summary, viruses have a protein capsid, not a capsule, which serves to protect their genetic material.

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