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What are the 4 DNA Viruses?

Published in Virology 2 mins read

While the reference lists several examples, here are four well-known DNA viruses:

  • Herpesviruses
  • Smallpox virus
  • Hepatitis B virus (HBV)
  • Adenoviruses

Understanding DNA Viruses

DNA viruses are a diverse group of viruses that use DNA as their genetic material. They replicate using a DNA-dependent DNA polymerase. The Baltimore classification system categorizes viruses based on their genome type and replication strategy. DNA viruses fall into groups I (dsDNA), II (ssDNA), and VII (dsDNA-RT).

Here's a brief overview of the four DNA viruses listed above:

  • Herpesviruses: This is a large family of viruses that cause a variety of diseases, including herpes simplex (oral and genital herpes), varicella-zoster virus (chickenpox and shingles), and Epstein-Barr virus (mononucleosis). Herpesviruses are characterized by their ability to establish latency, meaning they can remain dormant in the body for long periods and reactivate later.

  • Smallpox virus: This virus, a member of the Orthopoxvirus genus, caused the highly contagious and deadly disease smallpox. Thanks to a successful global vaccination campaign, smallpox was eradicated in 1980. However, stocks of the virus are still maintained in secure laboratories.

  • Hepatitis B virus (HBV): This virus causes hepatitis B, a liver infection that can lead to chronic liver disease, cirrhosis, and liver cancer. HBV is a unique DNA virus because it replicates through an RNA intermediate, using reverse transcriptase.

  • Adenoviruses: Adenoviruses are a common cause of respiratory illnesses, such as the common cold, as well as conjunctivitis (pinkeye), bronchitis, and pneumonia. They are typically mild and self-limiting, but can cause more severe illness in people with weakened immune systems.

In summary, Herpesviruses, Smallpox virus, Hepatitis B virus, and Adenoviruses are four diverse and significant examples of DNA viruses, each with unique characteristics and impacts on human health.

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