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What is Class A Flu?

Published in Virology 2 mins read

Class A flu is more accurately known as influenza A. It refers to influenza viruses of the A type, which are the only influenza viruses known to cause flu pandemics, meaning global epidemics of flu disease.

Understanding Influenza A

Influenza A viruses are distinct because they can infect humans and a variety of animals, including birds, pigs, horses, and other mammals. This ability to cross species boundaries is a key factor in the emergence of novel influenza strains.

Why Influenza A Causes Pandemics

The potential for pandemics arises when a new influenza A virus emerges that:

  • Infects humans.
  • Spreads easily from person to person.
  • Evades existing immunity in the human population.

Examples of Influenza A Viruses

Examples of influenza A subtypes that have caused pandemics include:

  • H1N1: The cause of the 1918 Spanish Flu pandemic and the 2009 Swine Flu pandemic.
  • H2N2: The cause of the 1957 Asian Flu pandemic.
  • H3N2: The cause of the 1968 Hong Kong Flu pandemic.

Influenza A vs. Other Influenza Types

There are other types of influenza viruses (B, C, and D), but influenza A stands out because of its pandemic potential. Influenza B can also cause epidemics, but generally causes milder disease than influenza A. Influenza C typically causes mild illness, and influenza D primarily affects cattle.

In summary, influenza A viruses are the influenza viruses most likely to cause widespread and severe disease outbreaks because of their ability to infect multiple species and rapidly evolve.

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